Selecting Patients for Cardiac Resynchronization Therapy

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Selecting patients for cardiac resynchronization therapy: electrical or mechanical dyssynchrony?

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Cardiac resynchronization therapy (CRT) reduces morbidity and mortality in patients with heart failure. International guidelines unanimously endorse QRS prolongation to identify candidates for implantation, based on over 4,000 patients randomized in landmark trials. Small, observational, nonrandomized studies with surrogate end points have promoted echocardiography as a superior method of patie...

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SEE PAGE 969 C ardiac resynchronization therapy (CRT) is a highly effective treatment for some patients with heart failure. Current guidelines recommend the implantation of CRT devices in patients with left ventricular (LV) dysfunction and electrical dyssynchrony, evidenced by a left bundle branch block (1). Unfortunately, not all patients suitable for CRT derive symptomatic benefit—an unsatisf...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2009

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2008.11.062